Pituitary Adenoma

Radiotherapy Guidelines

BHOC pituitary RT protocol

Radiotherapy guidelines, including EBRT and SRS, for treatment of pituitary adenoma

Non-Functioning Adenoma

Gamma Knife radiosurgery for the management of nonfunctioning pituitary adenomas: a multicenter study
Jason P. Sheehan, M.D., Ph.D., Robert M. Starke, M.D., M.Sc.,1 David Mathieu, M.D.,3 Byron Young, M.D.,4 Penny K. Sneed, M.D.,8 Veronica L. Chiang, M.D.,6 John Y. K. Lee, M.D.,7 Hideyuki Kano, M.D., Ph.D.,2 Kyung-Jae Park, M.D., Ph.D.,2 Ajay Niranjan, M.D., M.B.A.,2 Douglas Kondziolka, M.D.,2 Gene H. Barnett, M.D., M.B.A.,5 Stephen Rush, M.D.,9 John G. Golfinos, M.D.,9 and L. Dade Lunsford , M.D.
J Neurosurg 2013 119:446–456,

Multicentre series of >500 patients with NFA treated with SRS

Radiotherapy for pituitary adenomas: Long-term efficacy and toxicity
Sara C. Erridge, David S. Conkey, Diane Stockton, Mark W.J. Strachan d, Patrick F.X. Statham a, Ian R. Whittle a, Robin Grant a, Gillian R. Kerr e, Anna Gregor
Radiotherapy and Oncology 93 (2009) 597–601

Long term series of 385 patients with NFA treated with EBRT in Edinburgh

Outcome NF pituitary adenoma after first regrowth

a 2 UK centre overview of the results of what happens after regrowth- regarding further treatment and their outcomes. Use of radiotherapy appears to improve control


Review article of Cushing's Syndroma
Lacroix et al
Lancet 2015

Good overview of Cushing's Syndrome including Cushing's Disease-including pathophysiology and treatment

SRS in cushings- review
Sheenhan et al
J neurooncology 2019

Review article by Sheehan (Virginia) regarding the use of SRS in Cushings disease


Meta-analysis of srs in treatment of acromegaly

Met-analysis of the sure of SRS in the treatment of acromegaly by Sheehan (Virginia)