Episode 3, series 1. How I treat early breast cancer with radiotherapy
In this podcast Dr Jenner, breast cancer specialist in Bristol, discusses the role of radiotherapy in those with early breast cancer- both the evidence around this and the practicalities of how to set up the patient. Look out for the quiz question- how many breath holds to treat. The answer is 3-4, usually.
The Bristol Oncology Podcasts
How I treat early breast cancer with radiotherapy
Prime II study
Knuckler et al
Lancet Oncology 2015 16(3) 266-73
Study which randomised those >65Yr to RT or not after WLE
CALBG 9343
Hughes et al
JCO 2012 31 (19) 2382-7
Study randomising those >70Yr after WLE and tamoxifen to radiotherapy or not
Cochran’s review of boost radiotherapy
Kindts et al
2017
A Cochran’s review of the benefits of boost radiotherapy to the tumour bed after WLE and whole breast RT
Fast-Forward Trial
Brunt et al
Lancet 2020 395 1613-26
Hypofractionated breast radiotherapy: 1 v 3 weeks
Start Trial
Hauilad et al
Lancet Oncology 2013 14(11) 1086-94
Trial demonstrating that hypofractionated radiotherapy was equivalent to standard fractionated radiotherapy
Amarous Trial
Donker et al
Lancet 2014 15(12) 1303-10
trial randomising between surgery and radiotherapy after positive sentinel lymph node biopsy
Import Low Trial
Coles et al
Lancet 2017 390 10099 1048-60
Trial randomising between partial and full breast radiotherapy after WLE