Episode 3, series 1. How I treat early breast cancer with radiotherapy
In this podcast Dr Jenner, breast cancer specialist in Bristol, discusses the role of radiotherapy in those with early breast cancer- both the evidence around this and the practicalities of how to set up the patient. Look out for the quiz question- how many breath holds to treat. The answer is 3-4, usually.
The Bristol Oncology Podcasts
How I treat early breast cancer with radiotherapy
Prime II study
Knuckler et al
Lancet Oncology 2015 16(3) 266-73Study which randomised those >65Yr to RT or not after WLE
CALBG 9343
Hughes et al
JCO 2012 31 (19) 2382-7Study randomising those >70Yr after WLE and tamoxifen to radiotherapy or not
Cochran’s review of boost radiotherapy
Kindts et al
2017A Cochran’s review of the benefits of boost radiotherapy to the tumour bed after WLE and whole breast RT
Fast-Forward Trial
Brunt et al
Lancet 2020 395 1613-26Hypofractionated breast radiotherapy: 1 v 3 weeks
Start Trial
Hauilad et al
Lancet Oncology 2013 14(11) 1086-94Trial demonstrating that hypofractionated radiotherapy was equivalent to standard fractionated radiotherapy
Amarous Trial
Donker et al
Lancet 2014 15(12) 1303-10trial randomising between surgery and radiotherapy after positive sentinel lymph node biopsy
Import Low Trial
Coles et al
Lancet 2017 390 10099 1048-60Trial randomising between partial and full breast radiotherapy after WLE